Haifan Lin’s work is focused on the self-renewing mechanism of stem cells using Drosophila/mouse germline stem cells and human embryonic stem cells as models. He also studies germline development and stem cell-related cancers.
Dr. Lin received his B.S. from Fudan University (1982), Ph.D. from Cornell University (1990), and postdoctoral training at the Carnegie Institution of Washington. He joined the faculty of Duke University in 1994, where he rose to the rank of Full Professor. He founded and co-directed the Duke Stem Cell Research Program (2005-2006), and moved to Yale in 2006 to establish Yale Stem Cell Center.
Dr. Lin made key contributions to the demonstration of stem cell asymmetric division and the proof of the stem cell niche theory, and discovered the argonuate/piwi gene family and their essential function in stem cell self-renewal and germline development. He was a discoverer of PIWI-interacting RNAs (piRNAs)—a discovery hailed by Science as one of the ten scientific breakthroughs in 2006. He proposed and discovered the Piwi-piRNA guidance mechanism in epigenetic programming.
Dr. Lin’s past service to the ISSCR included the Membership Committee (2005-2008), Abstract Review Committee (2008, 2009), Chair of the 2011 Annual Meeting Program Committee and Chair of the Publication Committee (2009-2012). He led the establishment of the ISSCR journal “Stem Cell Reports”. His ongoing service includes the Board of Directors (2009-), the Outstanding Young Investigator Award Selection Committee (2009-), the Annual Meeting Program Committee (2010-), and the ISSCR Advisory Committee to Cell Stem Cell (2010-). He was a Speaker at the 2nd, 4th, 6th, 7th, and 11th ISSCR Annual Meetings.
Dr. Lin’s service outside the ISSCR includes the NIH study sections (1998-2005, 2007, 2012), NIH Director’s Pioneer Award Committee (2009), Advisory Board of the NIH-NHLBI Progenitor Cell Biology Consortium (2010-2012), Board of Directors of the Society of Chinese Biological Investigators (2002-2008), Advisory Council of RIKEN Center for Developmental Biology, Japan (2007-), Council of Society of Chinese Bioscientists in America (2008-2011), Medical Advisory Board of New York Stem Cell Foundation (2009-), International Review Committee of the Chinese Academy of Sciences (2008-), National Key Stem Cell Research Programs Planning Committee of the Chinese Ministry of Science and Technology (2010-), and Shantou University Council (2010-).
Dr. Lin has served on the Editorial Boards of Stem Cells (2005-2008), Cell Stem Cells (2007-), StemBook (2007-), Journal of Cell Biology (2009-), Current Opinion in Cell Biology (2009-), Biology of Reproduction (2009-2010), and Cell Research (2010-), and National Science Review (2013-). He was a Featured Editor of Nature Reports Stem Cells (2009).