COREdinates and WiCell Research Institute: Tools for Basic and Applied Stem Cell Biology

Session 1: COREdinates: Core Faculty Consortium

Stem cell core facilities test, validate and standardize new technologies. We created a network of pluripotent stem cell core facilities (Stem Cell COREdinates) to save time, prevent duplication of resources and increase sampling across institutions. Most of our member labs focus on pluripotent stem cell culture, iPSC generation, engineering, differentiation and clinical work. Our goal is to share our experiences with each other and the field as a whole. This year, six of our member labs will present talks ranging from the role that stem cell cores plays to advance science and ending with the path to develop stem cell therapeutics.

Session 2: Advancing Stem Cell Treatments: Building Better Models

This focus session will bring together academic, pharmaceutical industry, and cure advocacy researchers who work on a variety of neural and muscular disorders to discuss current research tools, iPS cell-derived models, and the fields unmet needs. ISSCR members interested in the development of stem cell disease models, including genetic reprogramming tools and screening mechanisms involved, will benefit from the opportunity to engage panelists with diverse and unique viewpoints.

Program

 

8:30 – 8:40 a.m.

Introductory remarks
Mark Tomishima, COREdinates/ Memorial Sloan-Kettering Cancer

8:40 – 10:00 a.m.

Part I: Speakers

  • Richard Gronostajski, University of Buffalo- “How Stem Cell Cores Can Help Your Science: examples from WNYSTEM”
  •   Jen Moore, RUCDR – “Do iPSC Colonies Arise from Multiple Founder Cells"
  •    Wenli Yang, University of Pennsylvania – “To clone or not to clone: generation of iPS cells by selection of pooled culture”
  •   Debbie French, Children’s Hospital of Philadelphia- “Hematopoietic Disease Modeling using iPSCs"
  • Sandra Engle, Pfizer – “The rapidly evolving world of genomic editing in human pluripotent stem cells."
  •  Stefan Irion, Sloan Kettering Institute – “The unpaved road – from academic to translational research”
9:40 – 10:00 a.m. Discussion
10:00 – 10:30 a.m. Break / Networking
10:30 – 11:00 a.m.

Part II: Interactive Panel Discussion

Moderator : Tenneille Ludwig, WiCell Research Institute 
  • Stem Cells Neural: Lorenz Studer, Sloan-Kettering Institute                    
  • Stem Cells Muscle: Michelle Calos, Stanford University                            
  • cGMP Banking and Testing: Derek Hei Waisman Biomanufacturing 
  • Glyn Stacey National Institute for Biological Standards and Controls (NIBSC)
  • Su-Chun Zhang, University of Wisconsin-Madison 
  • Cure Advocacy: Claudia Mitchell, Limb Girdle Muscular Dystrophy 2I Research Fund
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11:00– 11:45 a.m.

Panel and audience discussion

Moderator: Timothy Kamp, University of Wisconsin