Co-hosted by            

  • Genome Editing

    Danwei Huangfu, PhD, Memorial Sloan Kettering Cancer Center, USA

    Weizhi Ji, PhD, Yunnan Key Laboratory of Primate Biomedical Research, China

    Qi Zhou, PhD, Zoology Institute, Chinese Academy of Sciences, China

  • Stem Cells and Cell Fate Decisions

    Markus Grompe, MD, Oregon Health & Science University, USA

    Darrell Kotton MD, Boston University School of Medicine, USA

  • Stem Cells of the Mesodermal Lineage

    Gordon Keller, PhD, McEwen Centre for Regenerative Medicine Ontario Cancer Institute, Canada

    Il-Hoan Oh, MD, PhD, Catholic University of Korea, South Korea

    Jian Xu, PhD, Children's Medical Center Research Institute at UTSW, Pediatrics, USA

  • Road to the Clinic

    Olivia Kelly, PhD, ViaCyte, Inc., USA

    Paul Simmons, PhD, Mesoblast Ltd., Australia

    Zheng Qin Yin, MD, PhD, Southwest Hospital, Third Military Medical University, China

  • Pluripotent Stem Cells

    Hongkui Deng, PhD, Peking University, China

    Dong Wook Han, PhD, School of Medicine Konkuk University, South Korea

    Hitoshi Niwa, PhD, CDB RIKEN Laboratory for Pluripotent Studies, Japan

    Duanqing Pei, PhD, Guangzhou Institute of Biomedicine & Health, CAS, China

  • Panel Discussion: Modeling human development and disease: New horizons

    Danwei Huangfu, PhD, Memorial Sloan Kettering Cancer Center, USA

    Weizhi Ji, PhD, Yunnan Key Laboratory of Primate Biomedical Research, China

    Olivia Kelly, PhD, ViaCyte, Inc., USA

    Darrell Kotton, MD, Boston University School of Medicine, USA

Deng photo ORGANIZER1Hongkui Deng, Ph.D. is a Professor of Cell Biology and Principal Investigators of Center for Life Sciences at Peking University. He is also Director of Peking University Stem Cell Research Center. Dr. Deng’s laboratory works on cellular reprogramming and generation of functional human cells from pluripotent stem cells. Dr. Deng has published over 100 research articles, reviews and position papers in the arena of Stem Cell Biology and Viral Immunology.
Niwa PicHitoshi Niwa joined RIKEN Center for Developmental Biology (CDB) as PI of Laboratory for Pluripotent Stem Cell Studies. He has been studying the molecular mechanisms governing cellular pluripotency of mouse ES cells, especially focusing on the function of the transcription factor network.
Olivia G. Kelly held a postdoctoral fellowship at the University of California at Berkeley she where she explored signaling mechanisms that regulate the development of various tissues using a functional screening approach with insertional mutagenesis of embryonic stem cells. Upon joining ViaCyte, she was able to apply her knowledge of embryogenesis and stem cell biology to the development of an islet cell replacement therapy for diabetes. As ViaCyte’s Director of Cell Biology, Dr. Kelly is responsible for various aspects of the research and development program including stem cell differentiation, assay development and preclinical studies.
ZHOU photoDr. Qi Zhou’s research focuses on the mechanisms of reprogramming, differentiation and de-differentiation; cellular plasticity and totipotency of stem cells and somatic cells, with a goal of promoting the application of stem cells in regenerative medicine. The major achievements include: obtained the first healthy animal using iPSCs via the tetraploid complementary method; identified molecular markers for the evaluation of pluripotency levels of stem cells and the related regulatory mechanisms; established various types of human and mouse embryonic stem cell lines, as well as set up the Beijing Stem Cell Bank, etc.
Huangfu picDanwei Huangfu is an Assistant Professor at Memorial Sloan Kettering Cancer Center since September 2010. The current research of the Huangfu lab is focused on two areas, to understand the mechanisms that underlie the acquisition and the maintenance of the pluripotent state (reprogramming and self-renewal), and to develop new functional genetics approaches using human pluripotent stem cells (both embryonic stem cells and induced pluripotent stem cells) to study human development and disease. More information about her research can be found here.
Ji Weizhi photoProf. Weizhi Ji is currently the Professor and Chair of Yunnan Key Laboratory of Primate Biomedical Research. Prof. Ji’s lab reported the first gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting. His lab has established human, monkey, rabbit and mouse embryonic stem cell lines and adult stem cell lines. His study found the mechanism of embryonic stem cells differentiate into neural stem cells in vivo and the integration mechanisms in vitro. Now his research focuses on generation of transgenic monkeys, stem cell self-renewal mechanisms and stem cell replacement therapy research.
Grompe.Portrait.CasualProfessor Grompe is the Director of the Oregon Stem Cell Center and the Papé Family Pediatric Research Institute in the Department of Pediatrics at Oregon Health & Sciences University in Portland, Oregon, USA. His clinical practice focuses on metabolic diseases. His research has focused on the use of in vivo selection to enhance gene and cell therapy. The biology of intra- and extrahepatic liver stem cells and their use in therapeutic liver repopulation are a particular interest. His lab generated the Fah knockout mouse model of hereditary tyrosinemia and recently developed a method to repopulate Fah mutant livers with human hepatocytes.
Keller photoORGANIZERGordon Keller, PhD is a Senior Scientist at the University Health Network’s (UHN) Princess Margaret Cancer Centre, Professor at the University of Toronto and Director of UHN’s McEwen Centre for Regenerative Medicine. His studies are focused on deciphering the cues that direct pluripotent stem cells to make different cell types.
Dr. Kotton is Professor of Medicine and the founding Director of the Center for Regenerative Medicine (CreM) at Boston University and Boston Medical Center. Dr. Kotton is a pulmonary physician-scientist whose laboratory research program has focused for more than a decade on harnessing pluripotent stem cell models to define the genetic and epigenetic landscapes of lung cell fate, the mechanisms that establish those fates, and the approaches by which foregut endodermal lineages, such as lung, thyroid, and liver, can be derived de novo for disease modeling or treatment design.
Xu Jian(J140912014-9x13)_3Jian Xu, PhD., is an Assistant Professor and CPRIT Scholar in Cancer Research in the Children’s Research Institute at UT Southwestern Medical Center. Dr. Xu’s primary research interest is functional cancer genomics and epigenetics with a focus on blood stem cell development and malignancies.
Oh photoDr. Il-Hoan Oh is Professor and Chairman of the Department of Medical Lifescience, The Catholic University of Korea, College of Medicine. He is Director of the Catholic High-Performance Cell Therapy Center. He is Director of the Center for Evaluation of Stem Cell Therapeutics (Korean FDA). He is a Presidential advisor of the National Committee for Bioethics of Korea and President of the Korean Society of Stem Cell Research (KSSCR). His research interests include hematopoietic stem cells, leukemia, microenvironment, and mesenchymal stromal cells.

Zheng Qin Yin, MD, PhD, Southwest Hospital, Third Military Medical University, China
Zheng Qin Yin, MD, PhD, Southwest Hospital, Third Military Medical University, China