Preliminary Schedule (subject to change)


7:00 – 9:00 p.m.
Opening Session
7:00 – 7:15 Opening Remarks - Michele De Luca, University of Modena and Reggio Emilia, Italy
7:15 – 8:30 Keynote: Stem Cells in Cancer: Do They Matter?
John Dick, Campbell Family Cancer Research Institute, Ontario Cancer Institute,
Princess Margaret Hospital, University Health Network, Canada
8:30 – 10:00 p.m.
Opening Reception
9:00 a.m. – 12:00 p.m.
Tissue Homeostasis
9:00 – 9:10 Nancy Witty, ISSCR
9:10 – 9:15 Chair- Sally Temple, Neural Stem Cell Institute, USA
9:15 – 9:40 Wnt Signaling, Lgr5 Stem Cells and Cancer
Hans Clevers, Hubrecht Institute, Netherlands
9:40 – 10:05 Dissecting the Stem Cell Component of Precancerous Lesions
Frank McKeon, Jackson Laboratory for Genomic Medicine, USA 
10:05 – 10:30 Skin Stem Cells in Silence, Action and Cancer
Elaine Fuchs, Howard Hughes Medical Institute, The Rockefeller University, USA 
10:30 – 10:55
Refreshment Break
10:55 – 11:20 Mouse Spermatogenic Stem Cell Self-Renewal
Ben Simons, University of Cambridge, UK
11:20 – 11:45 Stem Cells: Lost in Translation
Sean Morrison, Children's Medical Research Institute at UT Southwestern, USA
11:45 – 12:10 From Cells to Networks - Principles of Vascular Pattern Formation
Holger Gerhardt, London Research Institute-Cancer Research UK, UK
12:10 – 2:00 p.m.
Lunch, Exhibits and Poster Viewing
2:00 – 5:00 p.m.
Cell Fate Control
2:00 – 2:05 Chair - Richard Young, Whitehead Institute for Biomedical Research, USA
2:05 – 2:30 Contribution of the Reprogrammed Vascular Niche to Stem Cell Self-Renewal and Organ Regeneration
Shahin Rafii, Cornell Medical College & Angiocrine Bioscience, USA
2:30 – 2:55 The Role of Epithelial Progenitors in Liver Injury
Markus Grompe, Oregon Health & Science University, USA
 2:55 –3:20 Reprogramming Approaches to Cardiovascular Disease 
Deepak Srivastava, The Gladstone Institute of Cardiovascular Disease and University of California, USA
3:20 – 3:45 p.m.
Refreshment Break
3:45 – 4:10  Human ES Cell Derived Midbrain Dopamine Neurons for Cell Therapy in Parkinson’s Disease
Lorenz Studer, Sloan-Kettering Institute for Cancer Research, USA
4:10 – 4:35 Towards Regenerative Medicine for Multiple Sclerosis
Robin Franklin, Wellcome Trust and MRC Cambridge Stem Cell Institute, UK
4:35 – 5:00 Genome Exchange in Human Oocytes
Dieter Egli, New York Stem Cell Foundation, USA
 5:00 – 5:30 Flow cytometry applications for isolating and analyzing complex heterogeneous stem cell cultures
Mirko Corselli, R&D Scientist, BD Biosciences
5:30 – 7:00 p.m.
Poster Presentation and Reception
9:00 a.m. – 12:00 p.m.
Cell Therapy
9:00 – 9:05 Chair - Michele De Luca, University of Modena and Reggio Emilia, Italy
9:05 – 9:30 Self-organization of Neural Structures in 3D Stem Cell Culture
Yoshiki Sasai, Center for Developmental Biology RIKEN, Japan
9:30 – 9:55 Regenerative Medicine from Bench to Bedside: Overcoming the challenges to restore vision
Graziella Pellegrini, University of Modena and Reggio Emilia, Italy
9:55 – 10:20 Interaction Between Mesenchymal Stromal Cells, Bioengineered Tissues and Organs, and Human body
Paolo Macchiarini, ACTREM Karolinska Institute, Sweden
10:20 – 10:45 a.m.
Refreshment Break
10:45 – 11:10  Phase I/II Cell Therapy Trial for Duchenne Muscular Dystrophy
Giulio Cossu, University College London, UK
11:10 – 11:35 Cell Based Therapeutics for Skeletal Applications
Frank Luyten, University Hospitals KU Leuven, Belgium
11:35 – 12:00 Secreted Factors and MicroRNAs Inducing Cardiac Regeneration
Mauro Giacca, International Centre for Genetic Engineering and Biotechnology, Italy
12:00 – 2:00 p.m.
Lunch, Exhibits and Poster Viewing
2:00 – 5:00 p.m.
Gene Therapy
2:00 – 2:05 Chair - Henrik Semb, Lund University, Sweden
2:05 – 2:30 Gene Therapy for Severe Immunodeficiencies
Bobby Gaspar, UCL Institute of Child Health, UK
2:30 – 2:55 Uncovering Hematopoietic Stem Cells Dynamics and Activity in vivo Through Vector Insertion Site Barcoding in Humans
Luca Biasco,San Raffaele Scientific Institute, Italy
2:55 – 3:20 Adaptive Immunodeficiency and Gene Therapy
Alain Fischer, CHU Necker INSERM U768, France
3:20 – 3:45 p.m.
Refreshment Break
3:45 – 4:10  Preclinical Genotoxicity Testing of Stem Cell Products
Christopher Baum, Hannover Medical School, Germany
4:10 – 4:35 Endogenous Retroelements, KRAB'n'KAP, and the Preservation of Stem Cell Transcriptional Dynamics
Didier Trono, École polytechnique fédérale de Lausanne EPFL, Switzerland
4:35 – 5:00 Genetic Engineering of Hematopietic Stem Cells
Luigi Naldini, San Raffaele Scientific Institute, Italy
9:00 a.m. – 12:00 p.m.
Defining Regenerative Mechanisms
9:00 – 9:05 Chair - Ronald McKay, Lieber Institute for Brain Development, USA
9:05 – 9:30 Commercial Stem Cells - the Lesson from the MSC Case
Paolo Bianco, Sapienza University of Rome, Italy
9:30 – 9:55 Molecular Regulation of Skeletal Muscle Stem Cells
Shahragim Tajbakhsh, Institut Pasteur, Stem Cells & Development, France
9:55 – 10:20 Dissecting the Stem Cell Niche for Therapeutic Targeting
David Sassoon, INSERM, Université de Pierre et Marie Curie-Sorbonne Universités, France
10:20 – 10:45 a.m.
Refreshment Break
10:45 – 11:10   Developing Human RPE Stem Cells for Retinal Repair
Sally Temple, Neural Stem Cell Institute, USA
11:10 – 11:35 Pluripotent Stem Cells in Disease Modeling
George Q. Daley, Children's Hospital Boston, Harvard Stem Cell Institute, Howard Hughes Medical Institute, USA
11:35 – 12:00 The Control of Hepatic Progenitor Cells for Liver Regeneration
Stuart Forbes, University of Edinburgh, UK
12:00 – 2:00 p.m.
Lunch, Exhibits and Poster Viewing
2:00 – 5:00 p.m.
Lineage Epigenetics
2:00 – 2:05 Chair - Cédric Blanpain, Université Libre de Bruxelles, Belgium
2:05 – 2:30 Systems Level Analysis of Hematopoiesis
Tariq Enver, UCL Cancer Institute, University College London, UK
2:30 – 2:55 Targeting Developmental Pathways in Stem Cells and Cancer Stem Cells
Frederic de Sauvage, Genentech Inc., USA
2:55 – 3:20 Characterizing Cell Heterogeneity and Metastasis Initiating Events in Human SCC
Salvador Aznar-Benitah, Institute for Biomedical Research (IRB), Spain
3:20 – 3:45 p.m.
Refreshment Break
3:45 – 4:10  Intratumoural Heterogeneity in Human Serous Ovarian Carcinoma
John Stingl, Cancer Research UK Cambridge Research Institute, UK
4:10 – 4:35 Regulation of Hematopoietic Stem Cells by de novo DNA Methyltransferases
 
Margaret Goodell, Baylor College of Medicine, USA
4:35 – 5:20 Closing Keynote – Directed Differentiation of Human Pluripotent Stem Cells
Gordon Keller, McEwen Centre for Regenerative Medicine/University Health Network, Canada
5:20 – 5:30 Closing Remarks – Michele De Luca and Ronald McKay

IMPORTANT DATES

2013 Meeting Dates:
September 15-18, 2013

Meeting Supporters: