Message from the President
The ISSCR has always had strong female leaders, and many of them are featured in the September and October editions of Stem Cell Reports.Full story
- 10 September, 2018
The ISSCR is soliciting nominations to honor exceptional and innovative research and support for young scientists, through its extensive awards program. It also invites members to nominate candidates to serve on the ISSCR board of directors.Full story
- 23 August, 2018
Harvard University, U.S.
Energizing for Renewed Focus
Many of us find time in the summer to reflect on work and recharge our batteries. Vacations, visits with friends, and time with family all help get away from everyday concerns in the lab and gain some perspective to inform the scientific path for the year ahead.
With renewed purpose and motivation comes challenges and questions. Are we investigating and advancing the most important questions in our field? Have new discoveries or tools suggested we change direction or even curtail our work because it is less relevant than before? These are tough questions as we cycle into a new academic year and envision next steps for our research.
stem cell researchTake a closer look
Gene Therapy: Treating the Cause, Not the Symptom
Gene therapy, CRISPR, and gene editing are all terms that are beginning to appear more frequently in headlines, and the concept of manipulating DNA inside cells – once found only in science fiction – is now reality. In this post, we discuss what gene therapy is, what is new and exciting in the field, and why the technology could change the way we treat certain diseases.
Stem Cells in the News
Media highlights in the field of stem cell research and its translation to the clinic.
20 September, SF Gate
5 September, The Scientist
2 September, Wired
A sampling of recent stem cell research commentaries, articles, and resources.
Featured Current Protocols in Stem Cell Biology Article
Establishing an Organotypic System for Investigating Multimodal Neural Repair Effects of Human Mesenchymal Stromal Stem Cells, Thakor, et al (2018).Current Prot. Stem Cell Biology, e58. doi: 10.1002/cpsc.58.
Cell Surface N-Glycans Influence Electrophysiological Properties and Fate Potential of Neural Stem Cells Yale, et al (2018), Stem Cell Reports.
- , Amsterdam
Seeking a job? Have a job opening? the ISSCR Job Board gives members discounts on job postings here and in the monthly Pulse e-newsletter.
Other Stem Cell Events
Opportunities for researchers from around the world to explore the latest discoveries in stem cell science and regenerative medicine.
ISSCR and policy news from around the world.
27 August, The Scientist
US Senate Passes Spending Bill Granting NIH $39.1 Billion
EDITORIAL: Safety Should be Paramount in iPS Cell Clinical Trials
31 July, Regulatory Focus
FDA and EMA to Hold Workshop on Breakthrough and PRIME Designations
Learn about ISSCR colleagues in the stem cell field from around the world.
Nils Pfaff, PhD
Feb 13, 2018
Hometown: Wilhelmshaven, Germany
Current residence: Düsseldorf, Germany
Graduate degree: PhD in Molecular Medicine from Hannover Medical School
Current position: Lab Head Preclinical Pharmacology, Bayer AG (Wuppertal, Germany)
What is the current focus of your research, and what do you find most rewarding about your work?
I am currently working in preclinical research in the Pharmaceuticals Division of Bayer. Apart from establishing iPSC-derived cells for target identification and validation, the main focus is in vivo pharmacology mostly in the therapeutic areas thrombosis and hemophilia. I really like the application-driven way of working in the (pharma) industry. It is great being involved in projects that always have the goal to improve the life of patients and being able to actually move these projects forward. It’s also fascinating to see how complex developing a new drug actually is and there is something new to learn every day.
What led you to become a scientist and to stem cell research?
I’ve always been interested in science. Back in high school I participated in a science club, which allowed me to work on smaller projects in a university lab during some of the vacations. At first I decided to study medicine but somehow realized I didn’t want to become a physician. That’s why I enrolled for Molecular Medicine (at Göttingen University, Germany), which turned out to be a great combination of science and medicine. When I started my PhD in 2008, iPS cells really were the hottest topic in biomedical research and the possibility to turn a skin cell into a stem cell into a blood/neuronal/cardiac cell was (and still is) just thrilling.
How do you spend your free time?
I regularly play football (soccer for the US folks…) and force myself to go running at least once a week. I also enjoy cooking (end eating, of course) a lot and have become a bit of a wine geek lately as well. Trying to stay in touch with friends and family is also very important for me.
What is something your peers would be surprised to learn about you?
I am a guitarist in a heavy metal band (the long hair is gone, though…) and regularly go to metal concerts and festivals.
What do you most value about your membership with the ISSCR?
Being member of the ISSCR is the best and easiest way to stay connected with the entire stem cell community and to permanently keep track of this still rapidly evolving field. Going to the annual meetings is always fun because you meet colleagues you haven’t seen for a whole year in most of the cases. Of course, the science presented is fascinating every time. Working in the ISSCR Industry Committee is a great way to discuss the industry’s perspective on translational aspects with the community – I think this dialogue is essential to bring effective stem cell-based therapies to patients.