Clinical Resources

Resources for physicians and ethics review boards.

Practical Advice for Physicians and Ethics Review Committees

With stem cell science rapidly progressing toward medical application, the number of clinical trials using stem cell-derived approaches is increasing, yet physicians and ethics / institutional review boards currently have little independent guidance on how to assess them. Stem cell-derived cellular interventions require a unique set of considerations that differ from those used to assess pharmacological drugs, so it’s essential that the physicians that run them and the ethics / institutional review boards that approve them are familiar with the appropriate questions to ask. The ISSCR's "Stem Cell-Based Clinical Trials: Practical Advice for Physicians and Ethics/Institutional Review Committees" provides background and fundamental questions for clinicians and ethics / institutional review committees to ask when considering running or reviewing early phase, cell-based clinical trials. The guide was developed by practicing physician-scientists and stem cell professionals on the ISSCR’s Clinical Translation Committee.

Stem Cell-Based Clinical Trials: Practical Advice for Physicians and Ethics / Institutional Review Boards


Cover image_Practical Guide