• Q&A: Stem Cells, Regenerative Medicine and Veterans

    November 06, 2014
    This week, nations around the world recognize Remembrance Day and Veterans Day. The ISSCR is proud of the role stem cell research is playing in advancing the field of regenerative medicine, which stands to benefit wounded servicemen and women. Dr. Anthony Atala, director of Wake Forest Institute for Regenerative Medicine, North Carolina, U.S.A., leads the consortium of researchers that make up the Armed Forces Institute of Regenerative Medicine (AFIRM). We spoke with him about the organization, which is working to develop advanced treatment options.
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  • October 8 is Stem Cell Awareness Day

    September 15, 2014
    The ISSCR celebrates Stem Cell Awareness Day on October 8 with a Stem Cells in Focus webcast entitled “The Science of Regenerative Medicine,” presented by PhD candidate Ben Paylor of the Canadian Stem Cell Network. The webinar will explore the basics of stem cell biology and will include three StemCellShorts*, voiced by stem cell experts Drs. Jim Till, Janet Rossant and Mick Bhatia, as well as a question and answer period.
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  • Connecting Genetics and Heart Disease

    August 05, 2014
    Scientists and clinicians have long suspected and recently confirmed that a person’s genetic makeup contributes to the likelihood of their having a heart attack. However, there has remained a gap between our knowledge of genetic indicators and medicine; a gap that Dr. Chad Cowan, of Harvard University, is trying to bridge with stem cell research.
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  • Hematopoietic Stem Cells: a New Transplant Paradigm for Multiple Sclerosis?

    June 06, 2014
    For years now, bone marrow transplants have been used to treat patients with leukemia and other blood disorders. The hematopoietic (blood-forming) stem cells present in bone marrow can restore a patient’s blood system after it has been devastated by chemotherapy or radiation. This same approach is now being tested in clinical trials for people with multiple sclerosis (MS) and other autoimmune diseases in the hope that providing brand new blood cells will reset the immune system to a healthy state.
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  • Stem Cells May Be Key to Curing Retinal Disease

    May 09, 2014
    A team of UK stem cell scientists, led by Dr. Robin Ali from UCL Institute of Ophthalmology in London, has developed a new strategy for repairing the retina by transplanting photoreceptor cells generated in the laboratory from embryonic stem cells. There is a good precedent for using stem cell therapy to repair eye damage. Transplanting corneal stem cells to repair chemical burns of the cornea has been very successful in restoring vision. But the retina – a multi-layered neural network – is a much more complicated structure, so repairing it poses greater challenges.
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  • Ramping up Discovery with Kidney Organoids

    April 04, 2014
    Although they conjure up images of science fiction, organoids are actually the quirky new name for mini, lab-grown models of human organs. Scientists are using pluripotent stem cells – the master cells that make any cell in the body – to create small buds of brain, thymus, liver, intestine, eye or kidney tissue that replicate some of the functions we find in these organs.
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  • Making Sense of Disease – In a Dish

    March 06, 2014
    Stem cell research is revolutionizing the way scientists study human disease in many ways. One of the most fascinating, is through the creation of human “diseases in a dish,” which are giving scientists a better way to study disease biology and test new drugs. Read how Dr. Kevin Eggan from the Harvard Stem Cell Institute is using this technology to better understand diseases such as amyotrophic lateral sclerosis (ALS) and schizophrenia.
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  • Exploring Endogenous Heart Repair and Regeneration

    February 13, 2014
    For the millions of people who suffer from heart attacks every year, the aftereffects are literally scarring. When the heart muscle dies from lack of blood, it is replaced by scar tissue, since the heart has very little regenerative capacity. This grim prospect is what stem cell scientists, like Dr. Deepak Srivastava, Director of Cardiovascular Disease and the Stem Cell Center at the Gladstone Institutes in San Francisco, are hoping to change.
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  • Newly Discovered STAP Cells Explained

    February 02, 2014
    You may have heard the news this week about exciting new developments in the field of stem cell research, published in the January 30 issue of Nature. A Japanese scientist, Dr. Haruko Obokata, and her colleagues demonstrated a new way to reprogram specialized stem cells from a newborn mouse to a “pluripotent” state; which is to say, the cells gained the ability to turn into any sort of cell in the body, much the same way embryonic stem cells can. Learn more about this discovery and its potential implications.
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  • Introducing "Stem Cells in Focus"

    January 15, 2014
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