• Chimeras: From Mythology to the Lab

    14 February, 2017
    In Greek mythology, the chimera is often described and depicted as a monster, as in this image, that represents impending disaster. While chimeras in Greek literature are fictional and symbolic, the concept of chimeras in science, simply defined as an organism made of cells from two organisms, are real, and they represent scientific progress and its potential to impact human health.
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  • Stem Cell Year-in-Review 2016

    11 January, 2017
    If we picked one word to define the past year in the stem cell field, it would have to be ‘therapy.’ While many important developments impacted the field, two that garnered significant public, political and scientific attention in 2016 were the proliferation of clinics using unproven stem cell “therapies,” and the steps forward in therapeutic modification of human oocytes (unfertilized eggs) through a process called mitochondrial replacement therapy (MRT).
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  • A CRISPR Method For Gene Editing: A Biomedical Breakthrough From a “Germ”

    14 December, 2016
    Bacteria. What do you think of when you hear this word? “Germs,” “antibiotics,” or “bleach” may come to mind, depending on the context. What about “powerhouse of scientific discovery?” That’s a string of words, but one that accurately describes the impact this single-celled organism is having on stem cell biology and human health.
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  • Stem Cell Soup – The Importance of Knowing What Is In It

    19 October, 2016
    “I don’t even know what’s in the soup,” was the shocking quote from the founder of a chain of clinics highlighted in a recent Associated Press article about the increasing prevalence of clinics offering unproven stem cell therapies. The “soup” referred to the mixture of cells and fluid he extracted from a patient’s fat for re-injection into the same patient’s knees, one of many “stem cell” procedures being tried for more than 20 diseases and conditions.
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  • Celebrating Stem Cell Awareness Day – October 12

    12 October, 2016
    The ISSCR joins organizations and individuals around the world in celebrating the cells that are the building blocks of life: stem cells. Unlike other cell types, stem cells are unspecialized cells uniquely capable of making copies of themselves (self-renewing), differentiating into specialized cell types, and helping to maintain some tissues in the human body.
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  • ISSCR’s Stem Cell Guidelines: A Commitment to Patients and the Public

    06 October, 2016
    Stem cell science is advancing at a pace greater than ever before, and researchers are making significant discoveries toward medical therapies to treat diseases and injuries - many of which currently have no cure. In May 2016, the ISSCR developed guidelines to help protect the integrity of stem cell research and assure the public that it will proceed efficiently and remain responsive to public interests.
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  • Modeling the development and disease of the human enteric nervous system takes guts… and stem cells

    05 May, 2016
    Question: What part of the nervous system has over 500 million neurons - the cells that transmit electrical or chemical signals throughout the nervous system and beyond - and regulates important bodily functions? Sounds like the brain, right? What if you knew that this part of the nervous system also spans approximately 30 feet in an average adult? That’s right, it’s the enteric nervous system (ENS). Never heard of it?
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  • Stem Cells Need Sleep, Too

    06 November, 2015
    Sleep is important for our body. With modest sleep deprivation it can be a struggle to function at our highest level and long term sleep deprivation, or disruption, can have significant health effects. It turns out that your sleep deprivation may also impact others…....if you are donating your hematopoietic stem cells.
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  • The Importance of Professional Guidelines

    10 August, 2015
    Professional guidelines provide a practical and ethical framework for decision making and instill a sense of responsibility and accountability. Learn more about the ISSCR's guidelines for stem cell research and clinical translation.
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  • Stem Cell Research: Promise, Progress & Hype

    30 July, 2015
    Summary of a panel discussion at the recent annual meeting of the International Society of Stem Cell Research in Stockholm, featuring international experts discussing the complex issues surrounding the sale and marketing of experimental stem cell treatments.
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  • Modeling Human Biology and Organoids: A Big Impact from a Miniature Tissue

    20 July, 2015
    Organoids, or miniature organs, are a relatively new model system that has emerged from stem cell research and are making a big impact. These laboratory-grown, three-dimensional, mini-organs are microscopically small and are started from stem cells. Within a specialized growth environment, the stem cells, either adult or embryonic, depending on the tissue needed, are stimulated to grow and specialize into specific types of organoids. Although they are not exact replicas of the adult organ, they do replicate many aspects and thus give us a model of human development that we would not otherwise have.
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  • Stem Cells and the Aging Brain

    06 July, 2015
    Summary of a panel discussion on stem cells and the aging brain involving a world-leading grouping of international stem cell scientists.
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  • Public Symposium: Stem Cells and the Aging Brain

    02 June, 2015
    At the ISSCR public symposium in Stockholm, stem cell scientists from Germany, Sweden and the U.S. will explore during a moderated panel discussion the role of stem cells in the brain during our lives from development and through adulthood. Panelists will discuss how scientists are investigating what happens to these cells as we age, how this knowledge is being used to guide new strategies to boost brain health and to develop therapies utilizing stem cells to treat diseases of the brain.
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  • An Exciting Strategy for Treating Sickle Cell Disease with Stem Cells

    28 May, 2015
    Stem cell researchers are getting closer to a new treatment for sickle cell disease, moving promising laboratory research into human clinical trials. Millions of people worldwide suffer from this hereditary disease.
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  • Stimulating The Body's Stem Cells to Treat Multiple Sclerosis

    15 May, 2015
    What if, in this dawning era of regenerative medicine, we could help the body heal itself? Not by replacing diseased or damaged cells, as is so often the paradigm in this field, but by stimulating the stem cells already present in a given tissue to differentiate and then repair the damage. No, this isn’t science fiction, like using one of Dr. McCoy’s futuristic devices from Star Trek to heal the injured Captain Kirk. This approach is now being assessed as a potential treatment for multiple sclerosis.
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  • What to Consider: Human Genome Germline Modification

    30 April, 2015
    In the past few days, you may have heard about new research describing the editing of the DNA sequence in human embryos. This new research raises critical scientific, social, legal and ethical questions to be addressed by all of us.
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  • Introducing A Closer Look at Stem Cells

    17 April, 2015
    Today, we welcome you to the blog’s new home, the expanded Closer Look at Stem Cells website (www.closerlookatstemcells.org). The website is a perfect complement to the “Stem Cells in Focus” blog, housing informational pages on basic stem cell biology, the process by which science becomes medicine, clinical trials and the use of stem cells in understanding and potentially treating specific health conditions.
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  • Malaria-in-a-Dish Paves the Way for Better Treatments

    06 February, 2015
    Massachusetts Institute of Technology (MIT) researchers have discovered a new way to model malaria using stem cells in a petri dish, which will allow them to test potential antimalarial drugs and vaccines.
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  • Q&A: Stem Cells, Regenerative Medicine and Veterans

    06 November, 2014
    This week, nations around the world recognize Remembrance Day and Veterans Day. The ISSCR is proud of the role stem cell research is playing in advancing the field of regenerative medicine, which stands to benefit wounded servicemen and women. Dr. Anthony Atala, director of Wake Forest Institute for Regenerative Medicine, North Carolina, U.S.A., leads the consortium of researchers that make up the Armed Forces Institute of Regenerative Medicine (AFIRM). We spoke with him about the organization, which is working to develop advanced treatment options.
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  • October 8 is Stem Cell Awareness Day

    15 September, 2014
    The ISSCR celebrates Stem Cell Awareness Day on October 8 with a Stem Cells in Focus webcast entitled “The Science of Regenerative Medicine,” presented by PhD candidate Ben Paylor of the Canadian Stem Cell Network. The webinar will explore the basics of stem cell biology and will include three StemCellShorts*, voiced by stem cell experts Drs. Jim Till, Janet Rossant and Mick Bhatia, as well as a question and answer period.
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International Society for Stem Cell Research
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Skokie, Illinois, USA 60077
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