ISSCR International Symposium
20-22 February 2019  |  Amsterdam, Netherlands

Stem Cells & Organoids in Development & Disease offers three days of insightful presentations and conversations around a research topic at the forefront of our field. Renowned keynote speakers Hans Clevers and Jürgen Knoblich will give the opening and closing talks; in between, hear from invited experts from around the globe, and abstract-selected speakers presenting their latest research. 

Pre-Meeting Session

Ethical and Policy Challenges of Organoid Research and Regenerative Medicine Applications  
08:00–11:30 Wednesday, 20 February (additional registration required)
Co-organized by EMBO, this forum will explore the regulatory and ethical considerations and guidelines for translating organoids and stems cells to the clinic. It will include informative talks featuring key regulators and policymakers from the European Union and perspectives from leading ethicists and scientists. It will conclude with a panel discussion regarding the ethical and regulatory challenges posed by the recent advances in the field of stem cell research. 

8:20–8:35: Welcome and Overview

Melissa Little, Murdoch Children's Research Institute, Australia

8:35–9:05 Keynote
Wolfgang Burtscher
Deputy Director-General for Research and Innovation
European Commission, Belgium

9:05–9:50 Speakers
Roger Barker, University of Cambridge, UK
Ana Sofia Carvalho, Institute of Bioethics, Catholic University of Portugal, Portugal
Arnold Kriegstein, University of California San Francisco, USA

9:50–10:15 Refreshment Break

10:15–10:50 Speakers
Jeremy Sugarman, Johns Hopkins University, USA
Annelien Bredenoord, University Medical Center Utrecht, Netherlands
Daniel Klimmeck, EMBO Journal, Germany

10:50 – 11:30 Panel Discussion
Hans Clevers, Hubrecht Institute, Netherlands

logo: EMBO Excellence in Life Sciences

Thursday, 21 February

09:00 – 10:30 Organoid and Tissue Regeneration I
Session Chair: James Wells
Speaker: Meritxell Huch, The Gurdon Institute, University of Cambridge, UK
Speaker: Karl Koehler, Indiana University School of Medicine, USA
Speaker: Marike Koning, Leiden University Medical Centre, Netherlands
Botond Roska, Institute of Molecular and Clinical Ophthalmology, Switzerland

10:30-11:00 Refreshment Break
11:00 –12:00 Organoid and Tissue Regeneration II
Session Chair: Calvin Kuo  
Speaker: Marta Roccio, University of Bern, Switzerland
Speaker: Weng Chuan Peng, Stanford University, USA
Speaker: Todd McDevitt, Gladstone Institutes, USA
Speaker: Andras Nagy, Lunenfeld-Tanenbaum Research Institute-Sinai Health System, Canada

12:00 – 14:00 Lunch and Posters
14:00 –15:30 Modeling Disease I
Session Chair: Eduard Batlle
Speaker: Melissa Little, Murdoch Children’s Research Institute, Australia
Speaker: Oded Kopper, The Hebrew University of Jerusalem, Israel
Speaker: Jerome Mertens, The Salk Institute for Biological Studies, USA 
Speaker: Toshiro Sato, Keio University, Tokyo, Japan

15:30 – 16:00 Refreshment Break
16:00 – 17:00 Modeling Disease II
Session Chair: Paola Arlotta  
Speaker: Hugo Snippert, University Medical Center Utrecht, Netherlands
Speaker: Alexander Rialdi, Ichan School of Medicine and Mount Sinai, USA
Speaker: Arnold Kriegstein, Department of Neurology, UCSF School of Medicine, USA
17:00 – 18:30 Reception

Wednesday, 20 February

Stem Cells & Organoids in Development & Disease
An ISSCR International Symposium
Research using organoids is rapidly advancing the field of stem cell science. This three-day program explores this groundbreaking technique and its implications for the future of healthcare. 
13:00–14:00 Opening Keynote
Speaker: Hans Clevers, Hubrecht Institute, Netherlands
14:00 –15:30 Recapitulating Developmental Processes I
Session Chair: Nissim Benvenisty 
Speaker: Anne Grapin-Botton, DanStem, University of Copenhagen, Denmark
Speaker: Apana Bhaduri, University of California San Francisco, USA
Speaker: Nicole Repina, University of California Berkeley, USA
Speaker: James Wells, Cincinnati Children’s Hospital Medical Center, USA
15:30-16:00 Coffee Break
16:00 –17:00 Recapitulating Developmental Processes II
Session Chair: Helen Blau  
Speaker: Nicole Prior, University of Cambridge, UK
Killian Hurley, Royal College of Surgeons in Ireland, Ireland
Paola Arlotta, Harvard University, USA

Friday, 22 February

09:00 – 10:30 Modeling cell interactions
Session Chair: Meritxell Huch
Speaker: Shahin Rafii, Weill Cornell Medical College, USA
Speaker: Elisa Giacomelli, Leiden University Medical Center, Netherlands
Speaker: Arti Ahluwalia, University of Pisa, Italy
Speaker: Calvin Kuo, Stanford University, USA

10:30-11:00 Refreshment Break
11:00 –12:30 Tissue engineering
Session Chair: Shahin Rafii  
Speaker: Matthias Lutolf, EPFL, Switzerland  
Speaker: Shukry Habib, King's College London, UK
Speaker: James Hudson, QIMR Berghofer Medical Research Institute, Australia
Speaker: Helen Blau, Stanford University, USA

12:30-14:00 Lunch and Posters
14:00–15:00 Panel discussion: The Challenge, Limitation, and Promise of Organoids 
Moderator: Hans Clevers
Panelists: Anne Grapin-Botton, Botond Roska, Melissa Little,  Aparna Bhaduri
15:00 – 16:00 Closing Keynote
Juergen Knoblich, IMBA Institute of Molecular Biotechnology, Austria