
Member Briefings: ISSCR Guidelines Update
Join members of the task force charged with updating the ISSCR Guidelines for a four-part digital meeting series. Member Briefings: ISSCR Guidelines Update will address the 2021 Guidelines and recent advances in the field, including innovations in early embryo models, chimeras, organoids, genome editing, and the translation of stem cell research. During the briefings, attendees will have the opportunity to discuss the changes being considered by the task force. Available to ISSCR members only.
Program
Briefing 1: Embryo Models, Embryo Research, and the 14-Day Rule
10 November, 2020
16:30 - 18:00 EST (view your time zone)
The first briefing in the series will highlight the discussions around and recommendations on in vitro research with embryos including integrated and non-integrated stem cell-based embryo models and the culture of human embryos. The briefing will conclude with approximately 40 minutes for questions from attendees and discussion with the task force members.

Robin Lovell-Badge, PhD
The Francis Crick Institute, UK

Janet Rossant, PhD
Gairdner Foundation/SickKids, Canada

Debra Mathews, PhD
Johns Hopkins University, USA
Briefing 2: Laboratory Research
11 November, 2020
16:00 - 17:30 EST (view your time zone)
The second briefing in the series will give an overview of the proposed changes to the categories of research and what type of research should and should not be reviewed and focus on specific areas of research involving chimeras and organoids. The briefing will conclude with approximately 40 minutes for questions from attendees and discussion with the task force members.

Robin Lovell-Badge, PhD
The Francis Crick Institute, UK

Amander Clark, PhD
University of California, Los Angeles, USA

Insoo Hyun, PhD
Case Western Reserve University School of Medicine, USA

Jürgen Knoblich, PhD
Institute of Molecular Biotechnology, Austria
Briefing 3: Genome Editing
18 November, 2020
16:00 - 17:30 EST (view your time zone)
The third briefing in the series will include presentations on new recommendations for preclinical and clinical research involving mitochondrial replacement techniques, somatic genome editing, and germline genome editing. The briefing will conclude with approximately 40 minutes for questions from attendees and discussion with the task force members.

Robin Lovell-Badge, PhD
The Francis Crick Institute, UK

R. Alta Charo, JD
University of Wisconsin, USA

Andy Greenfield, PhD
MRC Harwell Institute, UK

Luigi Naldini, MD, PhD
Università Vita-Salute San Raffaele, Italy
Briefing 4: Clinical Translation and Regulatory Approval
19 November, 2020
16:00 - 17:30 EST (view your time zone)
The final briefing in the series will include presentations on the new recommendations for preclinical and clinical research and the regulatory authorization of stem cell-based therapeutics. It will also include a presentation on recommendations for curbing unproven therapies and preventing the premature commercialization of stem cell-based interventions. The briefing will conclude with approximately 40 minutes for questions from attendees and discussion with the task force members.

Robin Lovell-Badge, PhD
The Francis Crick Institute, UK

Melissa Carpenter, PhD
ElevateBio/Carpenter Group Consulting, USA

Gail Naughton, PhD
Histogen, USA

Leigh Turner, PhD
University of Minnesota, USA