In 2008, the ISSCR released Guidelines for the Clinical Translation of Stem Cells that examined the scientific, clinical, regulatory, ethical, and societal issues that must be addressed to ensure that basic stem cell research is responsibly transitioned into appropriate clinical applications. These guidelines were reviewed and updated in 2016, and incorporated into the 2016 Guidelines for Stem Cell Research and Clinical Translation.
The 2008 guidelines called for rigorous standards in the development of stem cell therapies including stringent evaluation and oversight, a thorough informed consent process, and transparency in operations and reporting.
The ISSCR acknowledges financial support for development of the guidelines from the EUROCORES Programme EuroSTELLS, a European Science Foundation (ESF) initiative, supported by the European Commission, Sixth Framework Programme, under contract no. ERAS-CT-2003-980409. Research funding was provided by participating national organizations. EuroSTELLS is managed by the European Medical Research Councils (EMRC) at the ESF. The ISSCR also thanks the Alzheimer’s Research Foundation, The Ellison Medical Foundation, and the Juvenile Diabetes Research Foundation Beta Cell Replacement Advisory Committee for their generous financial support of the Task Force.
- A Cell Stem Cell article summarizing the essential elements of the document
- Appendix 1: Patient Handbook on Stem Cell Therapies