Message from the President
The ISSCR submitted comments to Brazil’s health regulatory agency (ANVISA) regarding the proposed regulations for advanced therapy medicinal products that urge national governments to “maintain rigorous review pathways to ensure that stem cell-based products conform to the highest standards of evidence-based medicine.”Full story
- 10 October, 2019
Polices created by legislators and regulators can have a profound impact on stem cell and biomedical research and the development of new treatments. The ISSCR has been working on several fronts to advocate for responsible stem cell research and its application. Read more about the recent ISSCR-led fly in to Washington D.C. for discussions with government officials and our consultations with Google to prevent the marketing of unproven stem cell therapies.Full story
- 7 October, 2019
Gladstone Institutes, U.S.
Polices created by legislators and regulators can have a profound impact on stem cell and biomedical research and the development of new treatments. The ISSCR has been working on several fronts to advocate for responsible stem cell research and its application. Read more about the recent ISSCR-led fly-in to Washington D.C. for discussions with government officials and our consultations with Google to prevent the marketing of unproven stem cell therapies.
stem cell researchTake a closer look
How Understanding Stem Cell Biology Can Improve Cancer Therapy Here’s what you can do about it.
Stem Cells in the News
Media highlights in the field of stem cell research and its translation to the clinic.
8 August, Stem Cell Xpress
CRISPR Gene Editing Is Being Tested in Human Patients, and the Results Could Revolutionize Health Care
6 August, Time
3 August, The Guardian
A sampling of recent stem cell research commentaries, articles, and resources.
On the cover: Mori et al. report a three-dimensional cell cultivation method for endometrial cancer stem-like cells collected from clinical specimens. The cover image depicts features of the cultured spheroid cells. Cells with high aldehyde dehydrogenase (ALDH) activity (depicted here in pink) show the characteristics of cancer stem cells and are resistant to paclitaxel (red elf). ALDH inhibitors including disulfiram (blue elf), and inhibitors of glucose transporter such as BAY876 (green elf), can suppress the characteristics of cancer stem cells. This is because ALDH-high cells depend on glycolysis, and especially glucose intake (brown elf). These inhibitors, in combination with paclitaxel, are found to block endometrial cancer proliferation. The cover art was conceptualized by Tatsuya Ishiguro, and the artwork was prepared by Hiroko Uchida.
Featured Current Protocols in Stem Cell Biology Article
A High-Throughput Screening Method to Identify Compounds Displaying Human Vascular Embryonic Toxicity, Rose et al. (2019), Current Protocols in Stem Cell Biology, 50, e93. doi: 10.1002/cpsc.93.
Induced 2C Expression and Implantation-Competent Blastocyst-Like Cysts From Primed Pluripotent Stem Cells, Kime et al (2019), Stem Cell Reports. doi:10.1016/j.stemcr.2019.07.011.
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Other Stem Cell Events
Opportunities for researchers from around the world to explore the latest discoveries in stem cell science and regenerative medicine.
Global Policy News
ISSCR and policy news from around the world.
25 July, Regulatory Focus
As Stem Cell Clinics Proliferate, Energy and Commerce Leaders Seek to Hear FDA’s Plan
26 July, Science
Trump Administration Releases Details on Fetal Tissue Restrictions
3 August, The Guardian
FDA First Human-Monkey Chimera Raises Concern Among Scientists
Learn about ISSCR colleagues in the stem cell field from around the world.
Mohamed Abou El-Enein, MD, PhD
Professor of Regenerative Medicine, Head of Clinical Development Platform and Group Leader, Charité – Universitätsmedizin Berlin