Disease Fact Sheet: Age-Related Macular Degeneration (AMD)
The death of RPE and photoreceptors, along with the presence of intact inner retinal cells, provides a potential rationale for cell replacement therapy for the outer retina and the RPE, which are the primary sites of damage and degeneration in AMD. Several approaches have been explored to replace macular RPE cells, with several clinical trials currently underway to evaluate the safety and efficacy of submacular RPE cell injections from a variety of sources.