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©2021 by The International Society for Stem Cell Research. All rights reserved.

No part of this document may be produced in any form without written permission of The International Society for Stem Cell Research.

Guidelines for the Field of Stem Cell Research and Regenerative Medicine

As a service to the field, the ISSCR develops guidelines that address the international diversity of cultural, political, legal, and ethical issues associated with stem cell research and its translation to medicine. The guidelines maintain and underscore widely shared principles in science that call for rigor, oversight, and transparency in all areas of practice. Adherence to these principles provides assurance that stem cell research is conducted with scientific and ethical integrity and that new therapies are evidence-based.

Responding to advances in science, the guidelines were updated in 2021 to encompass a broader and more expansive scope of research and clinical endeavor while maintaining the fundamental principles of the research and application. The 2021 guidelines include new recommendations to address the recent scientific advances involving embryos, stem cell-based embryo models, chimeras, organoids, and genome editing.

Accessing the 2021 ISSCR Guidelines for Stem Cell Research and Clinical Translation update, online or PDF file:

Use the Table of Contents on the left to navigate to each main section of the updated ISSCR Guidelines;

Visit the Key Topics, which are intended to assemble areas of the ISSCR Guidelines update related to the topic onto one page; and

Download a clickable PDF (top left on this page)

Consider attending the ISSCR 2021 Annual Meeting 21-26 June (virtually). This year's meeting kicks off with a special session updating attendees discussing recommendations in the ISSCR Guidelines update members of the task force. 

ISSCR's Guidelines for Stem Cell Research and Clinical Translation are strictly copyrighted by the society. Contact isscr@isscr.org for more information.