ISSCR News
T Cell Mass Production for Immunotherapy Offers New Potential Against Solid Tumors
Cancer immunotherapy using T cells has proven to be effective against certain blood and skin cancers but is less effective in tumors like colorectal cancer, which is one of the most frequent cancers worldwide. One primary consideration with T cell immunotherapy is that it needs to be tailored to each patient individually through time- and cost-intensive, procedures. The procedures involve isolation of a patient’s own T cells, their expansion and genetic engineering to target the cells towards the patient’s cancer cells. This complex process that limits the widespread availability of such treatments. Consequently, an “off-the-shelf” T cell immunotherapy – one that can be universally used safely in any person – that is safe and effective in a wide range of cancer patients, including patients with solid cancers, is highly desirable.
The ISSCR Recognizes Outstanding Poster Award Winners at the ISSCR 2026 Annual Meeting in Montreal
The International Society for Stem Cell Research (ISSCR) has recognized five outstanding scientists with Poster Awards at the ISSCR 2026 Annual Meeting, honoring innovative research spanning developmental biology, disease modeling, regenerative medicine, and functional genomics.
Selected from more than 1,300 scientific posters presented during the meeting, the awards recognize exceptional research and scientific communication. Winning posters were evaluated by senior stem cell scientists attending the meeting, underscoring the rigor and peer recognition behind the awards.
Stem Cell Strategy for Chronic Spinal Cord Injury Advances
New preclinical findings and updated clinical trial plans presented today at ISSCR 2026 highlight a tailored stem cell approach designed to overcome the long-standing barriers of chronic paralysis
New research presented today at the International Society for Stem Cell Research (ISSCR) 2026 Annual Meeting highlights a significant step toward developing a stem cell-based treatment for chronic spinal cord injury (SCI), a condition for which no effective restorative therapy currently exists.
First Clinical Trial of Pluripotent Stem Cell-Derived Neural Stem Cells for Huntington’s Disease Highlighted at ISSCR 2026
Phase 1b/2a study marks an important milestone in the development of regenerative medicine approaches for Huntington's disease
An update on the first clinical trial evaluating a pluripotent stem cell-derived neural stem cell therapy for Huntington’s disease was presented today at the ISSCR 2026 Annual Meeting. The Phase 1b/2a REGEN4HD study represents a significant translational milestone following years of preclinical research, pivotal safety studies, regulatory engagement, and clinical trial development.
New Clinical Data Presented at ISSCR 2026 Demonstrate One-Year Survival of Stem Cell-Derived Neural Progenitor Cells in Patients with Retinitis Pigmentosa
New, previously unpublished clinical data was presented today at ISSCR 2026 demonstrating that transplanted human neural progenitor cells survived for at least one year following subretinal transplantation in patients with retinitis pigmentosa (RP), while maintaining a favorable safety profile.
Retinitis pigmentosa is a group of inherited retinal diseases that progressively causes vision loss currently has no treatment for most patients. Because thousands of different genetic mutations can cause the disease, developing mutation-specific gene therapies remains challenging. Cell-based therapies offer the potential for a gene-agnostic approach that could benefit a broader population of patients.
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